INSTRUMENTAL NEUTRON ACTIVATION ANALYSIS (INAA) AND LIQUID CHROMATOGRAPHY (LC) COUPLED TO HIGH RESOLUTION MASS SPECTROMETRY (HRMS) CHARACTERISATION OF SILDENAFIL BASED PRODUCTS SEIZED ON THE ITALIAN ILLEGAL MARKET

The commerce of illegal and copyright medicinal products on internet is a serious criminal problem.Drugs for erectile dysfunction such as phosphodiesterase type 5 inhibitor are the most commonly counterfeited medicines in Europe.The search of possible toxic chemical substances in seized products is needed.Moreover, the profiling of the material can

Rhubarb is an important ingredient in traditional Chinese medicine known as Rhei radix et rhizome.However, this common name refers to three different botanical species with different pharmacological effects.To facilitate the genetic identification of these three species for their more precise application in Chinese medicine we here want to provide